HBV Mutation Detail Information

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Mutation Information
Mutation Site L60V
Mutation Type Amino acid level
Gene/Protein/Region Type C
Literature Information
PubMed PMID 20959021
Published Year 2010
Journal Virology journal
Title Hepatitis B virus core protein with hot-spot mutations inhibit MxA gene transcription but has no effect on inhibition of virus replication by interferon α.
Author Zhijian Y,Zhen H,Fan Z,Jin Y,Qiwen D,Zhongming Z
Evidence In this study, we investigated whether HBc protein mutations at hot spots (L60V, S87G and I98L) could still inhibit MxA transcription and the potential significance of this inhibition in virus replication in vitro.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation