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Mutation Information
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Mutation Site
|
L60V |
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Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
C |
Literature Information
|
PubMed PMID
|
33946808
|
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Published Year
|
2021 |
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Journal
|
Microorganisms |
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Title
|
Conformational Plasticity of Hepatitis B Core Protein Spikes Promotes Peptide Binding Independent of the Secretion Phenotype. |
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Author
|
Makbul C,Khayenko V,Maric HM,Böttcher B |
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Evidence
|
With electron cryo microscopy, we provide novel structures for L60V and P5T and demonstrate that binding occurs at the tips of the spikes at the dimer interface, splaying the helices apart independent of the secretion phenotype.
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HBV Mutation Detail Information