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Mutation Information
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Mutation Site
|
L61I |
|
Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
BZLF1 |
|
Amino acid_Mutation
|
T102975G |
|
Country
|
North Africa;Asia;Oceania |
Literature Information
|
PubMed PMID
|
9466647
|
|
Disease
|
Nasopharyngeal carcinoma
|
|
Published Year
|
1998 |
|
Journal
|
International journal of cancer |
|
Title
|
Amino-acid change in the Epstein-Barr-virus ZEBRA protein in undifferentiated nasopharyngeal carcinomas from Europe and North Africa. |
|
Author
|
Grunewald V,Bonnet M,Boutin S,Yip T,Louzir H,Levrero M,Seigneurin JM,Raphael M,Touitou R,Martel-Renoir D,Cochet C,Durandy A,Andre P,Lau W,Zeng Y,Joab I |
|
Evidence
|
In 3 cases, there was a change fromaCtoaGatposition 102994, and, from a T toaGatposition 102975 in the other 4. These changes led to conservative amino-acid changes, with glutamic acid 54 being replaced by aspartic acid and leucine 61 by isoleucine respectively.
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