|
Mutation Information
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Mutation Site
|
L69A |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
Vpr |
Literature Information
|
PubMed PMID
|
32753492
|
|
Published Year
|
2020 |
|
Journal
|
mBio |
|
Title
|
HIV Vpr Modulates the Host DNA Damage Response at Two Independent Steps to Damage DNA and Repress Double-Strand DNA Break Repair. |
|
Author
|
Li D,Lopez A,Sandoval C,Nichols Doyle R,Fregoso OI |
|
Evidence
|
However, HIV-1 L64A/HIV-2 L69A was still able to recruit the DCAF1 adaptor protein, though at a slightly lower level than wild-type Vpr (Fig. 7A).
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