HBV Mutation Detail Information

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Mutation Information

Mutation Site	L80M
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Combined Mutation	rt.M204V+rt.L80M
Relevant Drug	lamivudine (LAM)
Country	Turkey

Literature Information

PubMed PMID	22224083
Disease	HBV infection
Published Year	2011
Journal	Hepatitis monthly
Title	Frequency and mutation patterns of resistance in patients with chronic hepatitis B infection treated with nucleos(t)ide analogs in add-on and switch strategies.
Author	Sayan M,Akhan SC,Senturk O
Evidence	Two patients in the add-on therapy group had sC137G amino acid substitutions (with rtL80M + rtM204I mutations), 2 patients in the switch therapy group had sG145R mutations (with rtN236T mutations), and 4 patients in the switch therapy group had sD144E mutations (1 patient with rtL80M + rtM204V mutations and 3 patients with rtQ215S mutations).

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation