|
Mutation Information
|
Mutation Site
|
L80V |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Combined Mutation
|
rt.M204I+rt.L80V+rt.L80I+rt.H55R |
|
Genotype/Subtype
|
C |
|
Country
|
China |
Literature Information
|
PubMed PMID
|
28440785
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2018 |
|
Journal
|
Antiviral therapy |
|
Title
|
Impacts of HBV rtH55R polymerase substitution on viral replication and rtM204I/V resistance to nucleoside/nucleotide antiviral drugs. |
|
Author
|
Xiang KH,Zhao CY,Wang S,Li Y,Su MZ,Wang QY,Xu XZ,Deng J,Zhuang H,Li T |
|
Evidence
|
Further analysis shown in Fig. 2Dindicated that rtH55R, rtL80I/V, rtV173L/M, rtL180M and rtL229F/M/V/W preferred to be coexisting with rtM204I/V substitution compared to the rtM204 group
|
|
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HBV Mutation Detail Information