HPV Mutation Detail Information

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Mutation Information

Mutation Site	L83V
Mutation Type	Amino acid level
Gene/Protein/Region Type	E6
Amino acid_Mutation	T350G
Genotype/Subtype	HPV16
Viral Reference	K02718.1

Literature Information

PubMed PMID	26318249
Published Year	2015
Journal	Virology
Title	The human papillomavirus 16 European-T350G E6 variant can immortalize but not transform keratinocytes in the absence of E7.
Author	Togtema M,Jackson R,Richard C,Niccoli S,Zehbe I
Evidence	To elucidate the functional effects of this polymorphism, we followed keratinocytes transduced with E-T350G E6 for over 60 passages and compared them to keratinocytes transduced, in parallel, with prototype or Asian-American (Q14H/L83V/H78Y) E6.

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation