|
Mutation Information
|
Mutation Site
|
L90M |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
PR |
|
Relevant Drug
|
saquinavir (SQV) |
Literature Information
|
PubMed PMID
|
16956392
|
|
Published Year
|
2006 |
|
Journal
|
Retrovirology |
|
Title
|
HIV-2 Protease resistance defined in yeast cells. |
|
Author
|
M'Barek NB,Audoly G,Raoult D,Gluschankof P |
|
Evidence
|
This functional assay allowed us to show for the first time that the L90M substitution, present in a primary HIV-2 isolate, modifies the HIV-2 Protease susceptibility to Saquinavir but not Lopinavir.
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HIV Mutation Detail Information