HIV Mutation Detail Information

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Mutation Information

Mutation Site	L90M
Mutation Type	Amino acid level
Gene/Protein/Region Type	PR
Combined Mutation	pr.L90M+pr.I84V
Viral Reference	K03455.1

Literature Information

PubMed PMID	17352531
Published Year	2007
Journal	PLoS computational biology
Title	A look inside HIV resistance through retroviral protease interaction maps.
Author	Kontijevskis A,Prusis P,Petrovska R,Yahorava S,Mutulis F,Mutule I,Komorowski J,Wikberg JE
Evidence	We then used the CLM to predict cleavability of the chosen 30 substrates by mutant HIV-1 proteases I84V, L90M, and I84V + L90M. (The outcome for the predicted cleavability of the 30 chosen substrates was essentially the same for the mutant HIV-1 proteases as for the HXB2 HIV-1 protease.)

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation