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Mutation Information
|
Mutation Site
|
L90M |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
PR |
|
Viral Reference
|
K03455.1
|
|
Relevant Drug
|
PIs |
|
Country
|
USA |
Literature Information
|
PubMed PMID
|
18221530
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2008 |
|
Journal
|
Retrovirology |
|
Title
|
Multiple independent origins of a protease inhibitor resistance mutation in salvage therapy patients. |
|
Author
|
Kapoor A,Shapiro B,Shafer RW,Shulman N,Rhee SY,Delwart EL |
|
Evidence
|
To determine if the common protease inhibitor resistance mutation L90M is only selected once or repeatedly on different HIV genetic backbones during the course of failed anti-viral therapies we analyzed a linked region of the viral genome during the evolution of multi-drug resistance.
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HIV Mutation Detail Information