|
Mutation Information
|
Mutation Site
|
L90V |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
E6 |
|
Genotype/Subtype
|
HPV16 |
|
Viral Reference
|
NC_001526
|
|
Country
|
China |
Literature Information
|
PubMed PMID
|
31670402
|
|
Disease
|
Cervical intraepithelial neoplasia
|
|
Published Year
|
2020 |
|
Journal
|
Journal of medical virology |
|
Title
|
Genetic variability and functional implication of HPV16 from cervical intraepithelial neoplasia in Shanghai women. |
|
Author
|
Zhao J,Zhu J,Guo J,Zhu T,Zhong J,Liu M,Ruan Y,Liao S,Li F |
|
Evidence
|
In the E6 gene, there were four silent mutations and nine missense mutations, resulting in eight amino acid changes (R5G, D32E, D32N, I34L, E36Q, H85Y, L90V, E120D), D32E (54/82, 65.85%) occurred frequently (Table S3).
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HPV Mutation Detail Information