|
Mutation Information
|
Mutation Site
|
L97A |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
PR |
Literature Information
|
PubMed PMID
|
33390426
|
|
Published Year
|
2020 |
|
Journal
|
Japanese journal of infectious diseases |
|
Title
|
A Single Amino Acid Substitution at HIV-1 Protease Termini Dimer Interface Significantly Reduces Viral Particles Processing Efficiency. |
|
Author
|
Chiang M,Wang C |
|
Evidence
|
The results showed that an alanine substitution for L97 (PRL97A) completely inhibited the proteolytic activity of protease.
|
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|