EBV Mutation Detail Information

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Mutation Information

Mutation Site	M140A
Mutation Type	Amino acid level
Gene/Protein/Region Type	BRLF1

Literature Information

PubMed PMID	21697476
Published Year	2011
Journal	Journal of virology
Title	Cellular transcription factor Oct-1 interacts with the Epstein-Barr virus BRLF1 protein to promote disruption of viral latency.
Author	Robinson AR,Kwek SS,Hagemeier SR,Wille CK,Kenney SC
Evidence	We find that Oct-1 interacts directly with BRLF1 in vitro and that a mutant BRLF1 protein (the M140A mutant) attenuated for the ability to interact with Oct-1 in vitro is also resistant to Oct-1-mediated transcriptional enhancement in 293 BRLF1-stop cells.

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation