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Mutation Information
|
Mutation Site
|
M184I |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Relevant Drug
|
NRTIs |
|
Country
|
Taiwan(China) |
Literature Information
|
PubMed PMID
|
30122963
|
|
Clinical information
|
Yes
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2018 |
|
Journal
|
Infection and drug resistance |
|
Title
|
HIV-1 genotypic drug resistance in patients with virological failure to single-tablet antiretroviral regimens in southern Taiwan. |
|
Author
|
Tsai HC,Chen IT,Lee SS,Chen YS |
|
Evidence
|
With EVG, T66I/A, E92G/V/Q, T97A or R263K (n = 16, 3, 2 and 1, respectively) arose by weeks 8-16, followed by 1-4 accessory mutations, conferring high-level resistance (> 100-fold) by week 36.
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