|
Mutation Information
|
Mutation Site
|
M184V |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Combined Mutation
|
rt.M184V+rt.K65R |
|
Relevant Drug
|
lamivudine (LAM);didanosine (DDI);abacavir (ABC);tenofovir (TNV) |
|
Country
|
USA |
Literature Information
|
PubMed PMID
|
20516563
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2010 |
|
Journal
|
Antiviral therapy |
|
Title
|
Clonal resistance analyses of HIV type-1 after failure of therapy with didanosine, lamivudine and tenofovir. |
|
Author
|
Barnas D,Koontz D,Bazmi H,Bixby C,Jemsek J,Mellors JW |
|
Evidence
|
Single genome sequencing was performed on nine failure samples containing both K65R and M184V mutations by standard genotype, either as wild-type/mutant mixtures (6/9) or as mutant only (3/9).
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HIV Mutation Detail Information