|
Mutation Information
|
Mutation Site
|
M184V |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Relevant Drug
|
nevirapine (NPV) |
Literature Information
|
PubMed PMID
|
32140396
|
|
Published Year
|
2020 |
|
Journal
|
Acta pharmaceutica Sinica. B |
|
Title
|
Synthesis and biological evaluation of a series of 2-(((5-akly/aryl-1H-pyrazol-3-yl)methyl)thio)-5-alkyl-6-(cyclohexylmethyl)-pyrimidin-4(3H)-ones as potential HIV-1 inhibitors. |
|
Author
|
Wu Y,Tang C,Rui R,Yang L,Ding W,Wang J,Li Y,Lai CC,Wang Y,Luo R,Xiao W,Zhang H,Zheng Y,He Y |
|
Evidence
|
Mutation site of HIV-1RF/V82F/184V are V82F and M184V in protease encoding region in pol gene.
|
|
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HIV Mutation Detail Information