|
Mutation Information
|
Mutation Site
|
M184V |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Genotype/Subtype
|
RF02_AG |
|
Viral Reference
|
K03455.1
|
|
Relevant Drug
|
NRTIs |
|
Country
|
Cameroon |
Literature Information
|
PubMed PMID
|
32692778
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2020 |
|
Journal
|
PloS one |
|
Title
|
Pre-treatment drug resistance and HIV-1 genetic diversity in the rural and urban settings of Northwest-Cameroon. |
|
Author
|
Fokam J,Takou D,Teto G,Nforbih SE,Kome OP,Santoro MM,Ngoufack ES,Eyongetah M,Palmer D,Fokunang ET,Fokunang CN,Colizzi V,Perno CF,Ndjolo A |
|
Evidence
|
Fifteen (15) PDR mutations were found among four patients the urban settings [6 resistance mutations to NRTIs:[M41L (2), E44D (1), K65R (1), K70E (1), M184V/I (2), K219R (1)] and 6 resistance mutations to NNRTIs: K103N (1), E138A/G (2), V179E (1), M230L (1), K238T (1), P225H (1)] against two (02) mutations found in two patients in the rural setting[2 resistant mutations to NNRTIs: E138A (1) and Y188H (1)].
|
|
|