HIV Mutation Detail Information

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Mutation Information

Mutation Site	M184V
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Relevant Drug	NRTIs;lamivudine (LAM);emtricitabine (FTC);tenofovir (TDF)
Country	Zambia

Literature Information

PubMed PMID	32804970
Disease	HIV infection/AIDS
Published Year	2020
Journal	PloS one
Title	Prevalence and characteristics of HIV drug resistance among antiretroviral treatment (ART) experienced adolescents and young adults living with HIV in Ndola, Zambia.
Author	Miti S,Handema R,Mulenga L,Mwansa JK,Abrams E,Frimpong C,Burke VM,Zulu M,Siwingwa M,Mwakazanga D,Kalibala S,Denison JA
Evidence	The mutation M184V which confers resistance to NRTI drugs of lamivudine (3TC) and emtricitabine (FTC) was the most common (81%) among NRTI associated mutations followed by K65R (34.5%) which is associated with both tenofovir disoproxil fumarate (TDF) and tenofovir alafenamide fumarate (TAF) resistance.

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation