|
Mutation Information
|
Mutation Site
|
M1I |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
PreS2 |
|
Viral Reference
|
AB697502;
AB246345;
JQ801515;
AB246346;
JQ801516;
AB246339;
AB900105;
AB246342 |
|
Immune Escape
|
Y |
|
Country
|
Japan |
Literature Information
|
PubMed PMID
|
30584239
|
|
Disease
|
HBV infection
|
|
Published Year
|
2018 |
|
Journal
|
Scientific reports |
|
Title
|
Expansion of viral variants associated with immune escape and impaired virion secretion in patients with HBV reactivation after resolved infection. |
|
Author
|
Inuzuka T,Ueda Y,Arasawa S,Takeda H,Matsumoto T,Osaki Y,Uemoto S,Seno H,Marusawa H |
|
Evidence
|
Furthermore, reactivated HBV in 11 of 16 (69%) non-HSCT cases possessed substitutions associated with impaired virion secretion, including E2G, L77R, L98V, T118K, and Q129H in the S region, and M1I/V in the PreS2 region.
|
|
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HBV Mutation Detail Information