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Mutation Information
|
Mutation Site
|
M204I |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Relevant Drug
|
lamivudine (LAM) |
Literature Information
|
PubMed PMID
|
16448607
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2006 |
|
Journal
|
Gastroenterologia y hepatologia |
|
Title
|
[Lamivudine and adefovir resistance in a patient with HBeAg negative chronic hepatitis B]. |
|
Author
|
Mateos ML,Tato M,Moreira V |
|
Evidence
|
We have studied a 49-year-old patient with a HBeAg-negativeChronic hepatitis Bin whom, after 34 months of treatment with lamivudine and associated with an increase in the serum hepatitis B virus (HBV) DNA, the lamivudine resistance mutations M204I and L180V were detected.
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