HBV Mutation Detail Information

> M204I Search Result

Mutation Information

Mutation Site	M204I
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Relevant Drug	lamivudine (LAM)

Literature Information

PubMed PMID	16856618
Disease	Chronic hepatitis B
Published Year	2006
Journal	Antiviral therapy
Title	The clinical impact of early detection of the YMDD mutant on the outcomes of long-term lamivudine therapy in patients with chronic hepatitis B.
Author	Paik YH,Han KH,Hong SP,Lee HW,Lee KS,Kim SO,Shin JE,Ahn SH,Chon CY,Moon YM
Evidence	Cumulative viral breakthrough rates at 3 years was 75.0% and 14.3% in patients who had the rtM204I mutant and wild-type virus at 3 months, respectively (P=0.002).

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation