|
Mutation Information
|
Mutation Site
|
M204I |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Genotype/Subtype
|
B;C |
|
Viral Reference
|
X02763.1
|
|
Relevant Drug
|
lamivudine (LAM) |
Literature Information
|
PubMed PMID
|
17258721
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2007 |
|
Journal
|
Gastroenterology |
|
Title
|
Identification of a hepatitis B virus S gene mutant in lamivudine-treated patients experiencing HBsAg seroclearance. |
|
Author
|
Hsu CW,Yeh CT,Chang ML,Liaw YF |
|
Evidence
|
A polymerase mutation (rtM204I) occurred concomitantly in patient 9, which was likely responsible for the higher HBV-DNA level in this patient.
|
|
|
HBV Mutation Detail Information