|
Mutation Information
|
Mutation Site
|
M204I |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Genotype/Subtype
|
B;C |
|
Relevant Drug
|
lamivudine (LAM) |
|
Country
|
Taiwan(China) |
Literature Information
|
PubMed PMID
|
17400303
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2007 |
|
Journal
|
Antiviral research |
|
Title
|
Adefovir dipivoxil treatment of lamivudine-resistant chronic hepatitis B. |
|
Author
|
Dai CY,Chuang WL,Hsieh MY,Lee LP,Huang JF,Hou NJ,Lin ZY,Chen SC,Hsieh MY,Wang LY,Tsai JF,Chang WY,Yu ML |
|
Evidence
|
The distribution of pre-treatment LAM-resistant YMDD variants was: rtM204I:18 (62.1%) and rtM204V:11 (37.9%).
|
|
|
HBV Mutation Detail Information