HBV Mutation Detail Information

> M204I Search Result

Mutation Information

Mutation Site	M204I
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Amino acid_Mutation	G743C
Genotype/Subtype	A
Relevant Drug	lamivudine (LAM)
Country	Brazil

Literature Information

PubMed PMID	18171343
Disease	Chronic hepatitis B
Published Year	2008
Journal	Journal of gastroenterology and hepatology
Title	Lamivudine resistance and other mutations in the polymerase and surface antigen genes of hepatitis B virus associated with a fatal hepatic failure case.
Author	Bottecchia M,Ikuta N,Niel C,Araujo NM,O KM,Gomes SA
Evidence	RESULTS: A peak of alanine aminotransferase and aspartate aminotransferase levels occurred after 19 months of lamivudine treatment, associated with the rtM204I mutation.

Contents
Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation