|
Mutation Information
|
Mutation Site
|
M204I |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Relevant Drug
|
clevudine (CLV);entecavir (ETV) |
|
Country
|
Korea |
Literature Information
|
PubMed PMID
|
21484144
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2011 |
|
Journal
|
Hepatology international |
|
Title
|
A comparison of 48-week treatment efficacy between clevudine and entecavir in treatment-naïve patients with chronic hepatitis B. |
|
Author
|
Shin SR,Yoo BC,Choi MS,Lee DH,Song SM,Lee JH,Koh KC,Paik SW |
|
Evidence
|
Two (3.4%) patients in clevudine group showed virologic breakthrough with rtM204I mutation using direct sequencing analysis.
|
|
|
HBV Mutation Detail Information