|
Mutation Information
|
Mutation Site
|
M204I |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Genotype/Subtype
|
E |
|
Viral Reference
|
X75664.1
|
|
Relevant Drug
|
zidovudine (AZT) |
Literature Information
|
PubMed PMID
|
22195774
|
|
Clinical information
|
Yes
|
|
Disease
|
HBV-HIV coinfection
|
|
Published Year
|
2011 |
|
Journal
|
BMC research notes |
|
Title
|
Emergence of HBV resistance to lamivudine (3TC) in HIV/HBV co-infected patients in The Gambia, West Africa. |
|
Author
|
Stewart B,Jobarteh ML,Sarge-Njie R,Alabi A,de Silva T,Peterson K,Peterson I,Whittle H,Rowland-Jones S,Jaye A,Cotten M,Mendy M |
|
Evidence
|
A 10th patient was excluded because the patient's virus had the M204I mutation at the initiation of HAART and further investigation revealed that this patient had previously been on zidovudine AZT/3TC dual therapy when the mutation was likely to have emerged.
|
|
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HBV Mutation Detail Information