|
Mutation Information
|
Mutation Site
|
M204V |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Relevant Drug
|
lamivudine (LAM) |
Literature Information
|
PubMed PMID
|
15134177
|
|
Published Year
|
2004 |
|
Journal
|
Antiviral therapy |
|
Title
|
Comparisons of the HBV and HIV polymerase, and antiviral resistance mutations. |
|
Author
|
Bartholomeusz A,Tehan BG,Chalmers DK |
|
Evidence
|
Primary resistance to lamivudine occurs at rtM2041/V in the C Domain of the polymerase. Recently, resistance to adefovir has also been described in the D Domain at rtN236T.
|
|
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HBV Mutation Detail Information