|
Mutation Information
|
Mutation Site
|
M204V |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Relevant Drug
|
lamivudine (LAM) |
|
Country
|
Korea |
Literature Information
|
PubMed PMID
|
15932365
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2005 |
|
Journal
|
Alimentary pharmacology & therapeutics |
|
Title
|
Changes in different regions of hepatitis B virus gene in hepatitis B 'e' antigen-negative patients with chronic hepatitis B: the effect of long-term lamivudine therapy. |
|
Author
|
Buti M,Jardi R,Rodriguez-Frias F,Valdes A,Schaper M,Esteban R,Guardia J |
|
Evidence
|
YMDD mutations were observed in nine cases and both, L180M and M204V/I mutations were simultaneously detected in six cases.
|
|
|