HBV Mutation Detail Information

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Mutation Information

Mutation Site	M204V
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Relevant Drug	lamivudine (LAM)

Literature Information

PubMed PMID	15980328
Disease	Chronic hepatitis B
Published Year	2005
Journal	Antimicrobial agents and chemotherapy
Title	Emergence of a novel mutation in the FLLA region of hepatitis B virus during lamivudine therapy.
Author	Pai SB,Bozdayi AM,Pai RB,Beker T,Sarioglu M,Turkyilmaz AR,Grier J,Yurdaydin C,Schinazi RF
Evidence	The virus with rtM204V can also acquire rtL180M change and these are the most common genotypes seen in the clinic in response to long term lamivudine therapy.

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation