|
Mutation Information
|
Mutation Site
|
M204V |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Genotype/Subtype
|
A |
|
Relevant Drug
|
lamivudine (LAM) |
Literature Information
|
PubMed PMID
|
18036104
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2007 |
|
Journal
|
Liver international : official journal of the International Association for the Study of the Liver |
|
Title
|
Efficacy of hepatitis B virus (HBV) vaccination in treating lamivudine-resistant HBV reactivation following hepatitis B surface antigen seroconversion. |
|
Author
|
Gérolami R,Borentain P,Colson P,Norguet E,Gérolami A,Tamalet C |
|
Evidence
|
Due to the presence of rtM204V resistance mutation, lamivudine was not reintroduced and the patient was treated by HBsAg vaccination.
|
|
|
HBV Mutation Detail Information