|
Mutation Information
|
Mutation Site
|
M204V |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Genotype/Subtype
|
D |
|
Relevant Drug
|
lamivudine (LAM);tenofovir (TDF) |
Literature Information
|
PubMed PMID
|
21159112
|
|
Disease
|
Liver cirrhosis
|
|
Published Year
|
2011 |
|
Journal
|
Transplant infectious disease : an official journal of the Transplantation Society |
|
Title
|
Prevention of lamivudine-resistant hepatitis B recurrence after liver transplantation with entecavir plus tenofovir combination therapy and perioperative hepatitis B immunoglobulin only. |
|
Author
|
Karlas T,Hartmann J,Weimann A,Maier M,Bartels M,Jonas S,Mössner J,Berg T,Tillmann HL,Wiegand J |
|
Evidence
|
A 48-year-old male patient with hepatitis B-induced decompensatedLiver cirrhosis initially improved on lamivudine (LAM) until LAM resistance (rtL180M and rtM204V) emerged followed by renewed decompensation.
|
|
|