|
Mutation Information
|
Mutation Site
|
M204V |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Combined Mutation
|
rt.L180M+rt.M204V |
|
Genotype/Subtype
|
C |
|
Viral Reference
|
AY090460;
AF405706;
X75663;
X75664;
AY090453;
AF461359;
AB073858;
AY128092 |
|
Relevant Drug
|
lamivudine (LAM) |
|
Country
|
China |
Literature Information
|
PubMed PMID
|
27446286
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2016 |
|
Journal
|
Experimental and therapeutic medicine |
|
Title
|
Association between clinical features and YMDD mutations in patients with chronic hepatitis B following lamivudine therapy. |
|
Author
|
Ma Y,Yuan Y,Ma X,Tang B,Hu X,Feng J,Tian L,Ji Y,Dou X |
|
Evidence
|
Two patients with rtM204V + rtL180M belonged to genotype C and another patient with rtL180M alone belonged to genotype D.
|
|
|
HBV Mutation Detail Information