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Mutation Information
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Mutation Site
|
M204V |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Genotype/Subtype
|
A;B;C;D |
|
Relevant Drug
|
lamivudine (LAM);telbivudine (LDT);adefovir dipivoxil (ADV);tenofovir (TNF);entecavir (ETV) |
|
Country
|
Canada;Italy;South Korea;China;Indonesia;United States;Turkey |
Literature Information
|
PubMed PMID
|
29713126
|
|
Published Year
|
2018 |
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Journal
|
World journal of gastroenterology |
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Title
|
Naturally occurring hepatitis B virus reverse transcriptase mutations related to potential antiviral drug resistance and liver disease progression. |
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Author
|
Choi YM,Lee SY,Kim BJ |
|
Evidence
|
Eight mutations in RT (rtL80I, rtD134N, rtN139K/T/H, rtY141F, rtM204I/V, rtF221Y, rtI224V, and rtM309K) are significantly associated with HCC progression.
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HBV Mutation Detail Information