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Mutation Information
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Mutation Site
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M204V |
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Mutation Type
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Amino acid level |
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Gene/Protein/Region Type
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RT |
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Combined Mutation
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rt.M204V+rt.M204I+rt.L180M+s.C69*+rt.S78T;rt.M204V+rt.L180M+s.C69*+rt.S78T;rt.M204V+rt.M204I+rt.T184A+rt.L180M+s.C69*+rt.S78T;rt.M204V+rt.T184A+rt.L180M+s.C69*+rt.S78T;rt.M250L+rt.M204V+rt.M204I+s.C69*+rt.S78T;rt.N236T+rt.M204V+rt.A181T+rt.L180M+s.C69*+rt.S78T |
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Country
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China |
Literature Information
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PubMed PMID
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31398372
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Disease
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Chronic hepatitis B
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Published Year
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2019 |
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Journal
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Antiviral research |
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Title
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Investigation of hepatitis B virus (HBV) rtS78T/sC69* mutation in a large cohort of chronic HBV-infected patients with nucleoside/nucleotide analogue treatment. |
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Author
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Luo D,Liu Y,Chen R,Niu M,Liu L,Li X,Li Q,Huang B,Wang J,Xu D,Lin S |
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Evidence
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For patient C, mutants rtL180M + T184A + M204V (48%), rtM204V (14%), rtS78T/sC69* + L180M + T184A (9%), rtS78T/sC69* + L180M + T184A + M204V (9%), rtS78T/sC69* (5%), and rtS78T/sC69* + M204V (5%) were detected in sample C1 at the end of ETV therapy.
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HBV Mutation Detail Information