HIV Mutation Detail Information

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Mutation Information

Mutation Site	M41L
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Relevant Drug	NRTIs
Country	Portugal

Literature Information

PubMed PMID	32121161
Disease	HIV infection/AIDS
Published Year	2020
Journal	Viruses
Title	Molecular Epidemiology of HIV-1 Infected Migrants Followed up in Portugal: Trends between 2001-2017.
Author	Pimentel V,Pingarilho M,Alves D,Diogo I,Fernandes S,Miranda M,Pineda-Pena AC,Libin P,Martins MRO,Vandamme AM,Camacho R,Gomes P,Abecasis A
Evidence	Overall, among the 144 DN patients with TDR to NRTI (14,2%;95% CI: 12.1%-16.4%), associated with low to high resistance to a drug according to the Stanford HIV database algorithm v 8.4, the most prevalent mutations (>=10% of individuals harboring mutations) were M184V (n = 24;25%), M41L (n = 14;15%), T215F/Y/S (n = 12;13%).

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Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation