|
Mutation Information
|
Mutation Site
|
M46L |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
PR |
|
Genotype/Subtype
|
CRF35_AD;A1 |
|
Country
|
Moshi;Kilimanjaro;Tanzania |
Literature Information
|
PubMed PMID
|
25003939
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2014 |
|
Journal
|
PloS one |
|
Title
|
HIV-1 pol diversity among female bar and hotel workers in Northern Tanzania. |
|
Author
|
Kiwelu IE,Novitsky V,Kituma E,Margolin L,Baca J,Manongi R,Sam N,Shao J,McLane MF,Kapiga SH,Essex M |
|
Evidence
|
In the protease gene, three subjects (7%) had M46I/L mutations. All subjects in this study had HIV-1 subtype-specific natural polymorphisms at positions 36, 69, 89 and 93 that are associated with drug resistance in HIV-1 subtype B
|
|
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HIV Mutation Detail Information