|
Mutation Information
|
Mutation Site
|
M46L |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
PR |
|
Viral Reference
|
K03455.1
|
|
Relevant Drug
|
PIs |
|
Country
|
China |
Literature Information
|
PubMed PMID
|
30961560
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2019 |
|
Journal
|
BMC infectious diseases |
|
Title
|
Diversity of HIV-1 genotypes and high prevalence of pretreatment drug resistance in newly diagnosed HIV-infected patients in Shanghai, China. |
|
Author
|
Wang Z,Zhang M,Zhang R,Liu L,Shen Y,Wang J,Lu H |
|
Evidence
|
PI resistance were detected in only two samples, being simultaneously resistant to ATV/r and LPV/r at a potential low level caused by M46I/L mutation. There was no HIV-1 strain resistant to DRV/r found in our study.
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