|
Mutation Information
|
Mutation Site
|
M46L |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
PR |
|
Relevant Drug
|
PIs |
|
Country
|
China |
Literature Information
|
PubMed PMID
|
32500372
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2020 |
|
Journal
|
Virus genes |
|
Title
|
Retrospective analysis of HIV-1 drug resistance mutations in Suzhou, China from 2009 to 2014. |
|
Author
|
Song Y,Hu J,He J,Dong C,Yuan Y,Li Y,Li R,Ya X |
|
Evidence
|
Five SDRMs were found in the identified 16 mutation sites, among which M46L and V82S were related to PIs in the MSM population infected by HIV-1 CRF01_AE, whereas L100I, P225H, and M230L were related to NNRTIs found in hospital patients (L100I and P225H) or the MSM population (M230L) infected by CRF07/08_BC. However, SDRMs in NRTIs were not detected.
|
|
|
HIV Mutation Detail Information