HIV Mutation Detail Information

> M46L Search Result

Mutation Information

Mutation Site	M46L
Mutation Type	Amino acid level
Gene/Protein/Region Type	PR
Relevant Drug	PIs
Country	African;American

Literature Information

PubMed PMID	33014372
Disease	HIV infection/AIDS
Published Year	2020
Journal	SAGE open medicine
Title	Virologic suppression in patients with a documented M184V/I mutation based on the number of active agents in the antiretroviral regimen.
Author	Mouradjian MT,Heil EL,Sueng H,Pandit NS
Evidence	One patient had a multidrug-resistant reverse transcriptase mutation present (Q151M) which conferred resistance to all available NRTIs. The frequency of historical plasma RNA resistance mutation to at least one drug among non-nucleoside reverse transcriptase inhibitors (NNRTIs), PIs, or INSTIs was 32%, 6%, and 4%, respectively.

Contents
Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation