|
Mutation Information
|
Mutation Site
|
M550A |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
P |
Literature Information
|
PubMed PMID
|
15469692
|
|
Published Year
|
2004 |
|
Journal
|
Journal of biochemistry and molecular biology |
|
Title
|
Increased DNA polymerase fidelity of the Lamivudine resistant variants of human hepatitis B virus DNA polymerase. |
|
Author
|
Hong YB,Choi Y,Jung G |
|
Evidence
|
From the f(ins) value analysis, it is evident that M550I and M550V exhibit higher fidelity values than the wild-type HBV DNA polymerase, while M550A exhibits similar fidelity values.
|
|
|
HBV Mutation Detail Information