|
Mutation Information
|
Mutation Site
|
M550I |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
P |
|
Relevant Drug
|
lamivudine (LAM);penciclovir (PCV);clevudine (CLV) |
Literature Information
|
PubMed PMID
|
10353255
|
|
Published Year
|
1999 |
|
Journal
|
Biochemical pharmacology |
|
Title
|
Sensitivity of L-(-)2,3-dideoxythiacytidine resistant hepatitis B virus to other antiviral nucleoside analogues. |
|
Author
|
Fu L,Liu SH,Cheng YC |
|
Evidence
|
When these single mutations were coupled with the M550V/I mutation, all the double mutants were resistant to those drugs.
|
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