|
Mutation Information
|
Mutation Site
|
M550I |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
P |
|
Relevant Drug
|
lamivudine (LAM) |
|
Country
|
Japan |
Literature Information
|
PubMed PMID
|
12445424
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2002 |
|
Journal
|
Journal of hepatology |
|
Title
|
Mutations of polymerase, precore and core promoter gene in hepatitis B virus during 5-year lamivudine therapy. |
|
Author
|
Suzuki F,Suzuki Y,Tsubota A,Akuta N,Someya T,Kobayashi M,Saitoh S,Arase Y,Ikeda K,Kumada H |
|
Evidence
|
Mutations in L526M, M550V and M550I in polymerase were found in seven, six and six patients, respectively.
|
|
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HBV Mutation Detail Information