HBV Mutation Detail Information

> M552I Search Result

Mutation Information

Mutation Site	M552I
Mutation Type	Amino acid level
Gene/Protein/Region Type	P
Combined Mutation	p.M552I+p.L528M
Relevant Drug	lamivudine (LAM)

Literature Information

PubMed PMID	10996115
Disease	Chronic hepatitis B
Published Year	2000
Journal	Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology
Title	In vivo dynamics and pathogenicity of wild-type and resistant Hepatitis B virus during long-term lamivudine monotherapy - a clinical note.
Author	Zöllner B,Stoehr A,Plettenberg A,Feucht H,Schröter M,Schäfer P,Laufs R
Evidence	Significant genotypic resistance was detectable after 68 weeks, indicated by a substitution of isoleucine for methionine at residue 552 (M552I).

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation