|
Mutation Information
|
Mutation Site
|
M552I |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
P |
|
Genotype/Subtype
|
A;D |
|
Relevant Drug
|
lamivudine (LAM) |
Literature Information
|
PubMed PMID
|
11050059
|
|
Clinical information
|
Yes
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2000 |
|
Journal
|
Hepatology (Baltimore, Md.) |
|
Title
|
Early detection of viral resistance by determination of hepatitis B virus polymerase mutations in patients treated by lamivudine for chronic hepatitis B. |
|
Author
|
Nafa S,Ahmed S,Tavan D,Pichoud C,Berby F,Stuyver L,Johnson M,Merle P,Abidi H,Trépo C,Zoulim F |
|
Evidence
|
Determination of viral genotype, precore mutants, and polymerase gene mutants (L528M, M552V, M552I) was performed using the research version of Lipa-HBV.
|
|
|
HBV Mutation Detail Information