HBV Mutation Detail Information

> M552I Search Result

Mutation Information

Mutation Site	M552I
Mutation Type	Amino acid level
Gene/Protein/Region Type	P
Relevant Drug	lamivudine (LAM)

Literature Information

PubMed PMID	11907436
Disease	Chronic hepatitis B
Published Year	2002
Journal	Transplantation
Title	Seroconversion after the addition of famciclovir therapy in a child with hepatitis B virus infection after liver transplantation who developed lamivudine resistance.
Author	Shapira R,Daudi N,Klein A,Shouval D,Mor E,Tur-Kaspa R,Dinari G,Ben-Ari Z
Evidence	Sixteen months later, lamivudine resistance developed; a mutation (M552I) was confirmed by sequencing through the YMDD locus of the HBV polymerase gene.

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation