|
Mutation Information
|
Mutation Site
|
M552V |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
P |
|
Combined Mutation
|
p.M552V+p.L528M |
|
Relevant Drug
|
lamivudine (LAM) |
Literature Information
|
PubMed PMID
|
10613749
|
|
Published Year
|
2000 |
|
Journal
|
Hepatology (Baltimore, Md.) |
|
Title
|
In vitro evaluation of hepatitis B virus polymerase mutations associated with famciclovir resistance. |
|
Author
|
Xiong X,Yang H,Westland CE,Zou R,Gibbs CS |
|
Evidence
|
The lamivudine-resistant mutations M552I, M552V, and L528M+M552V, which were previously shown to display 8- to 25-fold resistance to LAMTP, were less resistant (< or = 3.
|
|
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HBV Mutation Detail Information