|
Mutation Information
|
Mutation Site
|
M552V |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
P |
|
Relevant Drug
|
lamivudine (LAM) |
Literature Information
|
PubMed PMID
|
10996115
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2000 |
|
Journal
|
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology |
|
Title
|
In vivo dynamics and pathogenicity of wild-type and resistant Hepatitis B virus during long-term lamivudine monotherapy - a clinical note. |
|
Author
|
Zöllner B,Stoehr A,Plettenberg A,Feucht H,Schröter M,Schäfer P,Laufs R |
|
Evidence
|
Indeed, during the course of HBV-resistance the mutation M552I changed to L528M/M552V after an additional 19 weeks.
|
|
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HBV Mutation Detail Information