|
Mutation Information
|
Mutation Site
|
M552V |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
P |
|
Relevant Drug
|
lamivudine (LAM) |
Literature Information
|
PubMed PMID
|
12657823
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2003 |
|
Journal
|
Taehan Kan Hakhoe chi = The Korean journal of hepatology |
|
Title
|
[Natural YMDD motif mutations of HBV polymerase in the chronic hepatitis B virus infected patients]. |
|
Author
|
Shin YM,Heo J,Kim GH,Kang DH,Song GA,Cho M,Yang US,Kim CM,Park HK,Jang HJ |
|
Evidence
|
To detect YMDD mutants, YVDD (M552V), and YIDD (M552I), we used direct sequencing and the restriction fragment length polymorphism (RFLP) method.
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|
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HBV Mutation Detail Information