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Mutation Information
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Mutation Site
|
N126K |
|
Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
Gp41 |
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Genotype/Subtype
|
A;B;C |
Literature Information
|
PubMed PMID
|
32197300
|
|
Published Year
|
2020 |
|
Journal
|
Viruses |
|
Title
|
Structural and Functional Characterization of the Secondary Mutation N126K Selected by Various HIV-1 Fusion Inhibitors. |
|
Author
|
Yu D,Su Y,Ding X,Zhu Y,Qin B,Chong H,Cui S,He Y |
|
Evidence
|
Notably, some CHR mutations were frequently observed during escape selection and in T20-containing clinical therapy, such as N126K, E136G, E137K, S138A, and E154K.
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