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Mutation Information
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Mutation Site
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N160K |
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Mutation Type
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Amino acid level |
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Gene/Protein/Region Type
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Gp120 |
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Country
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China |
Literature Information
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PubMed PMID
|
29769530
|
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Disease
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HIV infection/AIDS
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Published Year
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2018 |
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Journal
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Emerging microbes & infections |
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Title
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Comparison of the genotypic and phenotypic properties of HIV-1 standard subtype B and subtype B/B' env molecular clones derived from infections in China. |
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Author
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Xie H,Nie J,Chen Q,Huang W,Wang Y |
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Evidence
|
Three pseudoviruses with a mutation at N160 (B01: N160D, QH0692.42: N160S, and SF162.LS: N160K) all showed a resistant phenotype for both NAbs. PGT145 (Fig. 3g) and CH01-04 (Fig. 3h-k) showed similar neutralizing activities, performing best against B_EU strains and worst against B'_CN strains.
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HIV Mutation Detail Information